Chemistry Department: David B. Cordes
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Education
2001 - 2005 University of California at Santa Cruz
Ph.D. in organic chemistry- September 2005
1997 - 2000 California State University – East Bay, Hayward, CA
CA teaching credential in chemistry and biology
1986 - 1990 Hunter College, City University of New York
B.A. Major in History and Special Honors Curriculum
Minor in English Literature
Research Interests
In my new position at Pacific University I plan to continue research in organic synthetic methodology with an emphasis on inexpensive and environmentally friendly methods for the synthesis of enantiomerically enriched products using chiral Lewis acid catalysts. In the field of sensor chemistry, I am interested in developing fluorescence-based sensing systems for metal ions in aqueous solutions. Both of these research areas have very practical applications. New “green chemistry” methods of organic synthesis are needed to more efficiently prepare medicines and materials without the use of toxic solvents and unwanted byproducts. At the same time, improved sensing chemistry makes it possible to better understand chemical systems of biomedical, industrial, and environmental significance. This is an exciting time in chemistry education and research, when experiences and initiatives both in the classroom and the laboratory are increasingly influenced by considerations of sustainability and the principles of environmental stewardship.
My general research interests include:
- Fluorescent Chemosensors and Biosensors
- Bioorganic Chemistry
- Catalysts and Methods for Asymmetric Synthesis
- Materials Science
- Science Education
Recent Publications
J. Suri, D.B. Cordes, F. Cappuccio, R.A. Wessling, B. Singaram, “Monosaccharide Detection with 4,7-Phenanthrolinium Salts: Charge-Induced Fluorescence Sensing” Langmuir, 2003, 19, 5145.
J. Suri, D.B. Cordes, F. Cappuccio, R.A. Wessling, B. Singaram, “Continuous Glucose Sensing with a Fluorescent Thin Film Hydrogel” Angewandte Chemie, International Edition, 2003, 47, 5857.
F. Cappuccio, J. Suri, D.B. Cordes, R.A. Wessling, B. Singaram, “Optimization of Pyranine Derivatives in Boronic Acid-Based Saccharide Sensing: Significance of Charge Interaction between Dye and Quencher in Solution and Hydrogel” Journal of Fluorescence, 2004, 14, 521.
D.B. Cordes, A. Miller, S. Gamsey, Z. Sharrett, P. Thoniyot, R. A. Wessling, B. Singaram, “Optical Glucose Detection Across the Visible Spectrum Using Anionic Fluorescent Dyes and a Viologen Quencher in a Two-Component Saccharide Sensing System”, Organic and Biomolecular Chemistry, 2005, 3, 1708-1713.
D.B. Cordes, S. Gamsey, Z. Sharrett, A. Miller, P. Thoniyot, R. A. Wessling, B. Singaram, “Fluorescence Sensing of Monosaccharides with Boronic Acid Substituted Bipyridinium Quenchers and Pyranine: The Effects of Quencher Charge”, Langmuir, 2005, 21, 6540-6547.
D.B. Cordes, T.M. Nguyen, T.J. Kwong, J.T. Suri, R.T. Luibrand, and B. Singaram, “Asymmetric Reduction of Ketones under Mild Conditions Using NaBH4 and TarB-NO2: An Efficient and Unusual Acyloxyborohydride Reducing System” European Journal of Organic Chemistry 2005, 24, 5289-5295.
D.B. Cordes, T.J. Kwong, K.A. Morgan, and B. Singaram, “Chiral Styrene Oxides from α-haloacetophenones Using NaBH4 and TarB-NO2, a Chiral Lewis Acid” Tetrahedron Letters, 2006, 47, 349-351.
D.B. Cordes, J.T. Suri, F.E. Cappuccio, J.N. Camara, S. Gamsey, Z. Sharrett, P.Thoniyot, R. A. Wessling, B. Singaram, “Two-Component Optical Sugar Sensing Using Boronic Acid Substituted Viologens and Anionic Fluorescent Dyes: Modulated Quenching with Viologen as a Method for Glucose Detection”, chapter in Topics in Fluorescence Spectroscopy, vol. 11, 2006.
D.B. Cordes, S. Gamsey, B. Singaram, “Fluorescent Quantum Dots with Boronic Acid Substituted Viologens to Sense Glucose in Aqueous Solution”, Angewandte Chemie, International Edition, 2006, 45, 3829-3832.
S. Gamsey, N.A. Baxter, Z. Sharrett, D.B. Cordes, M.M. Olmstead, R.A. Wessling, B. Singaram, “The effect of boronic acid-positioning in an optical glucose-sensing ensemble”, Tetrahedron, 2006, 62, 6321–6331.
P. Thoniyot, F.E. Cappuccio, S. Gamsey, D.B. Cordes, R.A. Wessling, B. Singaram, “Continuous Glucose Sensing with Fluorescent Thin-Film Hydrogels. 2. Fiber Optic Sensor Fabrication and In Vitro Testing” Diabetes Technology & Therapeutics, June 2006, Vol. 8, No. 3: 279-287.
J. Kim, J.T. Suri, D.B. Cordes, B. Singaram. "Asymmetric Reductions Involving
Borohydrides: A Practical Asymmetric Reduction of Ketones Mediated by
(L)-TarB-NO2: A Chiral Lewis Acid", Organic Process Research and Development, 2006, 10, 949-958.
D.B. Cordes, A. Miller, S. Gamsey, B. Singaram, “Simultaneous Use of Multiple Fluorescent Reporter Dyes for Glucose Sensing in Aqueous Solution”, Analytical and Bioanalytical Chemistry, 2007, 387, 2767–2773.
Submitted or in preparation:
M. Mangel, S. Duensing, C. Brown, D.B. Cordes, H. Peckham, M. Ramon, C.D. Rowe, S. Seagroves, A. Stephens, “An Innovative Model for Integrating Educational Theory and Practice into Science and Engineering Ph.D. Programs”.
Recent Presentations
227th American Chemical Society National Meeting, Anaheim, CA
“Enantioselective reduction of aryl and alkyl ketones using NaBH4 and TarB-X: A chiral Lewis acid” 2004
229th American Chemical Society National Meeting, San Diego, CA
“Highly enantioselective reduction of a-haloacetophenones using TarB-NO2 and NaBH4 under mild conditions” 2005
229th American Chemical Society National Meeting, San Diego, CA
“Fluorescence sensing of glucose with boronic acid substituted quenchers and ionic dyes” 2005
Bay Area Institute 2005 (CILS), San Francisco, CA
“Engaging High School Science Students in Science Policy: A Letter Writing Campaign” 2005
California State University – East Bay, Dept. of Chemistry Seminar Series
“Optical monosaccharide detection using anionic fluorescent dyes and boronic acid-modified viologen quenchers” 2005