Emphasizes the interrelationship between physiology, pathophysiology, neurology, and medicinal chemistry in the areas of pain response, migraine, anxiety, insomnia, Alzheimer's, and ADHD. The major drug classes and agents used clinically for the treatment of these disorders are introduced together with pertinent chemical properties/structure-activity relationship, and the pharmacology of drug classes and specific agents. While also discussing the athophysiologies leading to the separate phenomena of tolerance, dependence, or addiction. Pass/No Pass. 2.5 credits.